Effects of preoperative oral carbohydrate on postoperative discomfort in patients undergoing elective surgery: a meta-analysis of randomized controlled trials

Fasting is a standard preoperative procedure performed to prevent vomiting and pulmonary aspiration during anaesthesia surgery. However, fasting can cause postoperative physical psychological discomfort. Intake of oral carbohydrate (CHO) may mimic the intake food, which prevents We conducted meta-analysis evaluate effect safety CHO in adult surgical patients. Randomized controlled trials (RCTs) were searched for PubMed, EMBASE, Cochrane Library databases. A was calculate pooled size by using random-effects models. The satisfaction outcomes mouth dryness, hunger, thirst, pain severity, duration hospitalization, homeostatic model assessment insulin resistance (HOMA-IR), incidence nausea vomiting. infection. In total, 57 RCTs involving 5606 patients included. assessed 10-point visual analogue scale (0 = best, 10 worst). severity dryness (weighted mean difference [WMD]: −1.26, 95% CI: −2.36 −0.15), thirst (WMD: −1.36, −2.05 −0.67), hunger −1.66, −2.53 −0.80), −0.68, −1.01 −0.35), hospitalization −0.39 day, −0.66 −0.12), HOMA-IR −1.80, −2.84 −0.76) significantly lower group than control group. did not differ between groups. No recorded any Preoperative alleviate patient’s discomfort without concerns. Surgeons anaesthesiologists should strongly promote as strategy enhance recovery after surgery protocols.